Always Sanitize
If you have a fragile immune system, traveling by plane might be your worst nightmare. Being in a confined space with so many strangers means you are hanging out with a lot more bacteria than you like.
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Make sure to pack hand sanitizer or alcohol wipes, and wipe down your armrest, folding table, and anything else you might want to touch. You don't know just how many people have touched it before. Or if those people even sneeze into their elbows like responsible adults.
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Self Reliance
The staff is busy — mainly busy serving the dozens of other people on the plane. This means they come in contact with loads of other individuals who may have been less than sanitary.
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Try being as self-sufficient as possible and bring your own snacks. This way you are the only person handling them, and you also free yourself up from the confines of the crew's service schedule.